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SAM-e
Supports Joint Comfort
and a Positive Mood
by Source Naturals
In fibromyalgia patients, SAM-e has been
shown to reduce morning stiffness and
fatigue, while reducing pain, and improving
mental outlook.
More well known as a treatment
for depression and osteoarthritis, preliminary
research suggests that SAMe may be helpful
for fibromyalgia symptoms, as well. |
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SAM-e and Fibromyalgia
Preliminary studies have suggested that SAM-e may
be helpful for those with fibromyalgia. A small double-blind
study evaluated the effect of S-adenosylmethionine
(SAMe, or SAM-e) or placebo in 17 people with fibromyalgia,
11 of whom had depression. The number of tender points
decreased after SAMe but not placebo. Depression,
as assessed by two rating scales, improved after SAMe
but not placebo.
Another double blind trial studied the use of SAM-e
for fibromyalgia and found it to be helpful. In this
trial, 44 people with fibromyalgia took 800 mg of
SAMe or a placebo for 6 weeks. In comparison to the
control group who took a placebo, those taking SAM-e
had improvements in disease activity, such as pain
at rest, fatigue, morning stiffness, and mood. In
other respects, the SAMe group did no better than
the placebo group when it came to reduce tenderness
in their tender points.
Effective Joint Support
SAMe has been used in Europe for two decades for
joint support with positive results. Studies have
shown that the breakdown of SAMe generates sulfate
groups that help maintain joint cartilage. SAM-e also
helps to form proteoglycans, which are used to renew
the matrix of cartilage. Animal studies show that
it increased the production of cartilage-building
cells in joints and may help improve joint lubrication
also. One study proved that SAMe was more effective
than NSAIDs (non-steroidal anti-inflammatory drugs)
when it came to helping with pain associated with
osteoarthritis, with less side effects.
Promotes Mental Well-Being
Studies also show that SAMe helps support a positive
outlook. Although the mechanism by which SAMe promotes
mental well-being is not known, we do know it is able
to cross the blood-brain barrier, where it affects
the production of mood-boosting neurotransmitters.
Supplement Facts
Capsules per Container: 30 Tablets, 400 mg
Serving Size: One (1) Tablet
Servings per Container: 30
Suggested Use: One tablet, one to three times daily.
Take tablets on an empty stomach.
Supplement Facts for 400 mg
Tablet
Serving Size: 1 tablet(s) |
Amount per Serving |
% Daily Value |
SAM-e (S-adenosyl-L-methionine)
from 800 mg of SAMe disulfate tosylate |
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† |
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† Daily Value not established.
Other Ingredients: Cellulose, mannitol,
hydroxypropyl methylcellulose pthalate, citric acid,
sodium starch glycolate, glyceryl triacetate, modified
cellulose gum, stearic acid, colloidal silicon dioxide,
titanium dioxide and yellow ochre.
Suitable for vegetarians. Contains no
yeast, dairy, egg, gluten, soy or wheat. Contains
no sugar, salt, preservatives, or artificial flavor
or fragrance.
Warning: If you are pregnant or breastfeeding
consult your physician before using this product.
Sufferers of bipolar disorder shouldn’t use
SAMe unless under medical supervision. Those taking
anti-depressant medications should confer with their
physician before taking SAMe in place of or in addition
to those medications and they should continue to be
monitored. Some caution is advised in those who have
cancer due to the methylating properties of SAMe.
In a small percentage of people this product may cause
nausea which tends to subside with long-term use.
Do not use if either tamper-evident seal is broken
or missing. Keep out of the reach of children.
Manufactured by Source Naturals
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SAM-e
Supports Joint Comfort and a Positive Mood
by Source Naturals
30 Tablets, 400 mg
$28.95 - Discount Price
(Retail Price $43.98 - Save
34%)
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